Anti-RUNX2 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse

產(chǎn)品型號：K101309P

更新時(shí)間：2022-08-15

廠商性質(zhì)：生產(chǎn)廠家

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Anti-RUNX2 Polyclonal Antibody

英文名稱	Anti-RUNX2 Polyclonal Antibody
宿主	Rabbit
別名	AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;OSF-2;OSF2;PEA2aA;PEBP2aA
應(yīng)用	WB
稀釋比例	WB 1:500-2000.
交叉反應(yīng)	Human Mouse
蛋白分子量	56kDa
Gene ID	860
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human RUNX2
性狀	液體
Public Immunogen Range	A synthetic peptide of human RUNX2
Subcellular Locations	Nucleus
Swiss Prot	Q13950
克隆類型	Polyclonal Antibody
背景資料	Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.