Anti-c-fos Polyclonal Antibody
應(yīng)用 IHC
稀釋比例IHC 1:50-200.
交叉反應(yīng)Human

產(chǎn)品型號(hào)：K106457P

更新時(shí)間：2022-08-15

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Anti-c-fos Polyclonal Antibody

英文名稱(chēng)	Anti-c-fos Polyclonal Antibody
宿主	Rabbit
別名	FOS;G0S7;AP-1;p55
應(yīng)用	IHC
稀釋比例	IHC 1:50-200.
交叉反應(yīng)	Human
蛋白分子量	53kDa
Gene ID	2353
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human c-fos
性狀	液體
Public Immunogen Range	A synthetic peptide of human c-fos
Subcellular Locations	Cytoplasm Nucleus
Swiss Prot	P01100
克隆類(lèi)型	Polyclonal Antibody
背景資料	Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum