Anti-ALYREF Polyclonal Antibody
應(yīng)用WB IHC
稀釋比例WB 1:5000-8000. IHC 1:100-300.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號(hào)：K107490P

更新時(shí)間：2022-08-13

廠商性質(zhì)：生產(chǎn)廠家

訪問量：959

服務(wù)熱線

010-50973130

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體

標(biāo)簽抗體血清球蛋白 IgG Polyclonal Antibody Antibody Monoclonal Antibody 一抗內(nèi)參抗體膠體金標(biāo)記二抗生物素化二抗 RBITC熒光標(biāo)記抗體二抗 FITC熒光標(biāo)記抗體二抗免疫血清二抗純化抗體二抗 HRP標(biāo)記二抗免疫球蛋白抗原IgG二抗

查看全部產(chǎn)品

產(chǎn)品介紹

Anti-ALYREF Polyclonal Antibody

英文名稱	Anti-ALYREF Polyclonal Antibody
宿主	Rabbit
別名	ALY;ALY/REF;BEF;REF;THOC4;THO complex subunit 4
應(yīng)用	WB IHC
稀釋比例	WB 1:5000-8000. IHC 1:100-300.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	27kDa
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human ALYREF
Subcellular Locations	Nucleus Cytoplasm
Swiss Prot	Q86V81
克隆類型	Polyclonal Antibody
背景資料	Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability.

多克隆抗體

由于多克隆抗體通常包含抗某一抗原的不同表位的抗體，所以，在深固定的樣本中也會(huì)很好地發(fā)揮效應(yīng)，在石蠟包埋組織切片的染色中，多克隆抗體常選用。根據(jù)實(shí)驗(yàn)的不同需要，多克隆抗體應(yīng)用于相應(yīng)抗原的標(biāo)記。此外，在農(nóng)業(yè)生產(chǎn)中，多克隆抗體被用于農(nóng)藥殘留現(xiàn)場(chǎng)監(jiān)測(cè)；在臨床應(yīng)用中，多克隆抗體主要用于病原物的檢測(cè)、疾病的診斷及治療，如作為蛋白類免疫抑制劑用于移植反應(yīng)和自身免疫病的治療。

索萊寶公司創(chuàng)立于2004年是一家擁有大批專業(yè)研發(fā)人員，專注于生物產(chǎn)品不斷完善和創(chuàng)新的公司。我們產(chǎn)品覆蓋面廣，品質(zhì)可靠。在優(yōu)化試劑產(chǎn)品線的同時(shí)，經(jīng)過多年研發(fā)經(jīng)驗(yàn)的積累，也推出了新的抗體產(chǎn)品線。初期，大批科研人員精心設(shè)計(jì)，齊力設(shè)計(jì)出好的抗體產(chǎn)品；后期，質(zhì)檢工作者嚴(yán)格的質(zhì)量把控為我們保駕護(hù)航。終，在我們的共同努力之下，帶您見證索萊寶公司的又一奇跡。

運(yùn)輸說明：

極低溫產(chǎn)品：極低溫產(chǎn)品運(yùn)輸過程中加裝干冰運(yùn)輸。用干冰把產(chǎn)品包裹起來，再用泡沫盒密封，膠帶層層粘住泡沫盒，放入索萊寶的箱子，然后交付給合作快遞，安全快速高效放心的送客戶的手中，保證產(chǎn)品的性質(zhì)穩(wěn)定如一，為您的實(shí)驗(yàn)保駕護(hù)航。
低溫產(chǎn)品：低溫產(chǎn)品運(yùn)輸過程中加裝索萊寶冰袋運(yùn)輸。事先用冰袋把產(chǎn)品包裹起來，再使用泡沫盒密封，用膠帶嚴(yán)實(shí)密封泡沫盒，再放入索萊寶的箱子（保溫效果少可以持續(xù)一周），然后交付給合作快遞，安全快速高效放心的送客戶的手中，保證產(chǎn)品的性質(zhì)穩(wěn)定如一，為您的實(shí)驗(yàn)保駕護(hù)航。
常溫產(chǎn)品：常溫產(chǎn)品運(yùn)輸過程中無需加冰或者特殊包裝。產(chǎn)品由公司庫房人員快速配貨，準(zhǔn)確快速高效的快遞保證產(chǎn)品快速送達(dá)您的手中。

多克隆抗體

運(yùn)輸說明：

上一個(gè)：K107489PAnti-RPL18 Polyclonal Antibody